The National Science Foundation (NSF) created the Innovation Corps (I-Corps) program to help accelerate the transfer of academic research into the marketplace. The NSF teamed worked with leading entrepreneurs from Silicon Valley to apply the “lean launch” methodology to help faculty-based researchers understand markets for their technologies. In 2015, UW-Milwaukee and the UWM Research Foundation were awarded a three-year grant from NSF to bring this important program to Milwaukee, creating the first NSF I-Corps Site in Wisconsin. The Southeastern Wisconsin I-Corps Site fosters commercialization of applied academic research and faculty/student innovation; builds innovation/commercialization networks that supports faculty and/or student ventures; and broadens the pool of students and faculty fluent in Lean LaunchPad (LLP) methodology.